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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194918802306e498f14aa1aa8eb4a66a5e1fb5384f9274c33157729afe1faf9b' 
  AND token = '7rqF6pCkpcOlyVPMPmTHvWqyWFA9lrROqzfSFpNDIHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}