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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72994ed537b7a4e1d668e1876bdb53fe4c5a756d0895a05bef5b5e20093fd54' 
  AND token = 'w3+aLbU5kyPL9chM+dWsbza8aDdmjviFfjgYqrQMINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}