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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d3ee11ac9beef152999ce6ac552a531cec1b5090b6b36437191933c36f4d0e' 
  AND token = 'douSETxVhn1G0hGnKypNlNPzvVxEO3Qiu1oGJi1RjQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}