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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9065c87b4b7be2499f541ada06c31d5a01ac0f0728886bc5865d0f27adc10cad' 
  AND token = 'jtJCQfADByU4Vq56CtSay8nk0qjsQTjk/fRc5bGiaIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}