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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13ec44ac80974676cf8946b940dab7bd11a75a0a147a4294cde98011cc6ac103' 
  AND token = '6SdM+v57fz3AnbZ/1dTRAuruxce/z4flAVwTsNvKfp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}