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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7cfa7f30983f0ac84b088cf3e175fde5c3e134f9e612253e013d688a1842852' 
  AND token = 'cP3FkVDax/RJ2kwW6sdWL2242XO6oBRYaENEONZj1ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}