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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484645bbfd983fa3fa3d515c1ce00c0620ae1114fbaa2b6d11234171b354cbf8' 
  AND token = 'h+/yQCnRgrdP3H+hoN+F1CbHOtrOT6osRrFvvRb4/aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}