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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165c01e861c28bfd268a5f6ea801c78639be4251dd22f92bcbce490a67e9ab14' 
  AND token = '96KW7YcFCd3kgF5vUuCB1+eAGjxPF9h0aF7DVW7HTBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}