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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9597f6c728ade63eb004420a02993d73f487638962e4e2dc1ee71131c1cc7ca' 
  AND token = 'dCKEkMe5HDn4t7v6htKnIsqBr+HIynzHe/Yo7KFOhpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}