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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad710b628d19100662e496bb5ca191bd136a481c9b566acab8450319c281efc' 
  AND token = 'ys1eIFYYpvqSciocXj9ihshO+PMZIyqnd6Cdkqq/TaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}