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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae8125c05fd4541429e0c7903b58ea7a20f4e123a38f6982c793a3dc7eaa51c4' 
  AND token = 'cjxMpmnIAYdWlFaiSNV16N/TmKpv2vs9iS24Hd0Mt6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}