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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3087d3736ce64a3366b650dd04cb8442b8e46521c8fd44ecaed3e2bee39679c' 
  AND token = 'JhuaDWEDJqlZ6Xdf2bikHmorHu2zJb6ZhZ0Rpm+PnFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}