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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a071f87e19494ab4dd51c56b98dcbf5c13bed68f93ed61b09ecdaa13621b01b3' 
  AND token = '5pGAawHmoxg+m490NHzCSVja2iEKNNsUvng9Np08a8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}