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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7d85a9b1f36108c1b2d71228b0c6ebd786198835ab00771880870b2683a286' 
  AND token = '4jfGTtVHTaFCrE3qX/PFPYva/N67pMPjs39GeD2YfCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}