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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ff055931285678611974bdd79b9f9a481c1b70da7087af6520c1a2bd6b7bba' 
  AND token = 'EWnnoDT9i3YlT+dvfR2k74K/9/QF1VIeKsMAxK5YcgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}