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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f2bf531b291a4c335f9e8497b2142c942c2ac5ec874d7e8ee038d36e4f3fc4' 
  AND token = 'e9IHd+3DTpbG+HqOe6I5LG548kIBHFtD0LqEQ8olCHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}