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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc972be798de78983de8016a1f5c672b791a98fbd1e7dc2f36fc56a26a7dabf' 
  AND token = '3iQw2LsqIWyVQ5/Nuo0u0iMdMcSLOa5PIYot1IlWj5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}