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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da161c01a73015179d60287da94e1d2cff8284bfe72115f3faa5fee4003853a0' 
  AND token = '9MAhXLFWILNUOXkk/fzgdOiXFgxVJh8+5YAvkOkB1Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}