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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727c9a4f2183ab7996c873bef08bba5fe8d8cf9cafe71bf7e69f6655c9b1ef9f' 
  AND token = 'JvCjJUlAvCgpqXuF9kiPlBf08ncwDlPGm1IN8FSX1Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}