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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e4a7f127d3b8078a212efc571936e64a76e2fd1e5ad489f56f1cc72a30b943' 
  AND token = 'eO+RPXLDyaM3SNl87N9TeUYuXmc15xbdL8tHr4M4CxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}