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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17e62be7ebbf0703c3d5fea018f66191f1e2d468f38357e004c801fc6c9943e' 
  AND token = 'ibbSkNnXL9sJhLDYRWGSWQBoRLIJVYGf7C6m/B5E3a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}