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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9904274eb0f26e8d4af4fa920bbe8237b04d600a6133deb64a677b9af8efba90' 
  AND token = 'avQFA3uRcBVnqxu+DRziqAlLKT26D3qKwmLcYcEYmo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}