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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a43f99074dcb1f1f2ea0c59d8cd1232e7f22e22932da166e9832e312f73b3d68' 
  AND token = 'dmtnwxmsgX7d9KH1Q4kjTsX1LF0m4QARPh2JHh66p6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}