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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e566705426fbe07a1c220fe5b9ef7da65946bd5860ce5d16555751313e1282' 
  AND token = 'UU0TKR+ktAlbALtLF636K9FAEo+oo/oz7Hk2335cHD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}