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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e343c3fb9df6e6a45bfaf430c002ee1268f6bc759f724b71dc8c544e5e6b454' 
  AND token = 'OxpmZI6tUL/sp6AY0CpOtQGDjqWA/7z79eA/q6LhPXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}