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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a250eadfd733bad4bb6105e7ed8f95b2ff6914eb5c668671ef6ab1f7943ef728' 
  AND token = '2WAENFVxxZsgIiAnR5+O8x2pUQEfQW++fnjI1iTtGfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}