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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d64926c075bc27be7dde1fdb961ee7ffb23c054c1c55a3f993e8849060d347c' 
  AND token = '4jV5a3acTuc3p7d+zeo4pTQWe0GGVGH9TtBZjFQ2DsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}