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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4701eea48a2cd1ce4c15ca25e1f25fe73f232da6d64d01e80f54bfa305b1f60a' 
  AND token = 'i0gf1DxSGJ5v28Hvs/1/4Iy37U5u4Bw3mKIihcOuXao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}