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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b143d28a51bc349de38b6f4be9112545c32fe63bfda8dde879c6e23535c1a88' 
  AND token = 'HmqipNg9XVHn+pCHhgrzpE3V0bbxXHmSQZsedqglFhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}