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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8442dfff8576a599981e8b0662a8809308fda31762496350dc71188b7a8a2e15' 
  AND token = 'WVZUoivDcVXPvLQbbdvC/z566e6MTJ/LHrSJyTfvlgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}