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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec53184acc96e9372325c49c3e0b3c11f29ccb7e7532ee9440d8fa04d152665' 
  AND token = 'sERl5pcOexdcEz51E9nT5+MaFrWGVd0+Be0T1hhrlMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}