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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b80b52359eef83bff0309222490cf04d93969315a23cebe886e6bf01197a937' 
  AND token = 'ZwC0GHXr0hlyFxD2uFU8O4jynW90/yVnjaQgsUD4tEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}