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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e20e09716ebfd66b5c1a8794d24f565dfaa8a9cc96dc2ba57842467c6b9773' 
  AND token = 'bZB5kbrCk/GXd/FWSNG9fz30vxS6bt1ZZUWOlXucIE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}