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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b09acfb8bd0dd78fcd6d5f81258eee685e6e737946379af8297a1a0006e4d0b' 
  AND token = 'jR1Mgb8tGz05i8iVtyF7NaXtAGcVVJ4ik9rezKLRhlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}