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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb9b205e1be50d357d5c5e681af603e2f19e7aa56e5542d64026aa92a7601920' 
  AND token = 'dduB3xeW3pGevdWU0FIIIKV6XnY0+WlkmoEDudLk5K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}