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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '945c7e25acbe8653c50f22536271d98a327535ad01a0b4e7371538e7b3c66602' 
  AND token = 'wjru/7I/7MUTpMRa4Bb4j/fqUG1KRq2YSd4cZqI1DTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}