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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445c4acdd63694f6c7da9cd6783d1336a6498327b350dd42c710de72e7e3fd59' 
  AND token = 'uJMGhMklkV5N30j42pxIxcPfcKtjYzUY0OaCQdJddrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}