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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270b25f386e16bf1b2e77d29eea1f1086b0dce74c138c805e016760f0d16df29' 
  AND token = '2T15ELDD80v8NU0rsr8VR98vkmbNC4IO+wwaTAyWD7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}