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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6492b16fe24a728b12647b7e55ad5d1cdff11a309b333a988e2363461dfd94b6' 
  AND token = 'w636OFIw0YRVKkYpO+SIL9fDNcbkCNgPpOm5CJanWlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}