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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a104a6e3416236367d012a5651f3cee63ff74b0c5a8f80872ec8adadeb8b4b' 
  AND token = 'nSXQQc42JuS/u/WJd09r8L1UgaGr8hWPdRudvqA+I7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}