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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1147518540dd5a0bcb1f1734530fad823d20c05d590cfaafe4f88ce67a067b' 
  AND token = 'tq3fVVmuX6+sYL3qWeDqLkxDURPPpqHiekFNk5kv5Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}