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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4813ff919c92d6effe41e43cb63924eb08338c9cb745f18fd9c0d35f7cc456dc' 
  AND token = 'e4hZc7b+aor1KTmBQe/TXvlX7aJJjEbbt/GlLfxuoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}