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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e443e907764f3a8d8043300fad16a1a9c1c0a23bdd6959918f30a3e8b67cff' 
  AND token = 'f9Rq1QJnwvHMB7juTRWiqWA15io43ib9Hew2KHR8v/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}