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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f849f0ff5a1ad554722f0acee01269337177b7043ae9aace59440d9378b6a122' 
  AND token = 'pChqZTYIesi4Fh99lbSd5EoNzkB5yzikq0LcqDMgmZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}