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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79cf670dc8063424e72ee6b33cce97854209591cc781f56f885d26b8d16f87fb' 
  AND token = 'Dgv20I3icU8j8GzLg2LAIDGy8pzyT+5otISyP6tXtCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}