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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54b9e0c61b37cc209233de67dbe4ee3ab1f860af36e9540ead5b15d482e7ba79' 
  AND token = 'S5i1DB5d+WE6u2u3jOngoefN6iCSTrUT23xSH9EeSu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}