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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e38b39dd12468cb916257da9cf6a80619a0711f485715fa2b89bd0bbb29c6af' 
  AND token = 'Q9KN/BL25mTlpux+ThC82UCTYrR8IjiL4lo5+4BoaRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}