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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfdb16c8b09d90b15092cff06d5e4adce43208d0b605aa2e40d7d1b60f4da49a' 
  AND token = 'gHD3Lb15Vpvh0Z4JWuBahZ6yVxehNXK5MJtJIFq4WxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}