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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8e60a7e80a25d94115e8bbd56d4e5ed1196ccf5d548b9f0cf26c646949fb76' 
  AND token = 'tqPLC3v8wZpr69QKVBxhKCdCJkJ6f0/iKXJx/EqdOdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}