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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87acbdee20642f793d503a997af205bf0c51f39d13dc462101ce7ebdec882cc1' 
  AND token = '3ekFp9ll9Q9YA4V8yHywZBD9w3VlThr0zpmtwD2+aPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}